Mitochondrial mutations and their effects:
de Grey ADNJ. A proposed refinement of the mitochondrial free radical
theory of aging. BioEssays 1997; 19(2):161-166. PDF
de Grey ADNJ. A mechanism proposed to explain the rise in oxidative stress
during aging. J Anti-Aging Med 1998; 1(1):53-66. PDF
de Grey ADNJ. The mitochondrial free radical theory of aging. Austin, TX:
Landes Bioscience, 1999, 212pp, hardcover (ISBN 1-57059-564-X).
de Grey ADNJ. The non-correlation between maximum longevity and enzymatic
antioxidant levels among homeotherms; implications for retarding human
aging. J Anti-Aging Med 2000; 3(1):25-36. PDF
de Grey ADNJ. The reductive hotspot hypothesis: an update. Arch Biochem
Biophys 2000; 373(1):295-301. PDF
de Grey ADNJ. The reductive hotspot hypothesis of mammalian aging: membrane
metabolism magnifies mutant mitochondrial mischief. Eur J Biochem 2002;
269(8):2003-2009. PDF
de Grey ADNJ. Mitochondrial mutations in vertebrate aging. In: Oxidative
stress and aging: advances in basic science, diagnostics, and
intervention (R.G. Cutler and H. Rodriguez, eds.), World Scientific
Publishing, 2002, pp. 437-451. PDF
de Grey ADNJ. Mechanisms underlying the age-related accumulation of mutant
mitochondrial DNA. In: Genetics of mitochondrial
diseases (I.J. Holt, ed.), Oxford University Press, 2003, pp. 247-275. PDF
de Grey ADNJ. Mitochondria in homeotherm aging: will detailed mechanisms consistent with the evidence now receive attention? Aging Cell 2004; 3(2):77. PDF
de Grey ADNJ. Mitochondrial mutations in mammalian aging: an over-hasty about-turn? Rejuvenation
Res 2004; 7(3):171-174. PDF
de Grey ADNJ. Reactive oxygen species production in the mitochondrial matrix: implications for the mechanism of mitochondrial mutation accumulation. Rejuvenation
Res 2005; 8(1):13-17. PDF
de Grey ADNJ. The plasma membrane redox system: a candidate source of aging-related oxidative stress. AGE J Am Aging Assoc 2005; 27(2):129-138. PDF
de Grey ADNJ. Free radicals in aging: causal complexity and its biomedical implications. Free Radic Res 2006, in press. PDF
Other:
de Grey ADNJ. Incorporation of transmembrane hydroxide transport into the
chemiosmotic theory. Bioelectrochem Bioenerg 1999; 49(1-2):43-50. PDF
de Grey ADNJ. Biologists abandon Popper at their peril. BioEssays 2000;
22(2):206-207. PDF
de Grey ADNJ. A proposed mechanism for the lowering of mitochondrial
electron leak by caloric restriction. Mitochondrion 2001; 1(2):129-139. PDF
de Grey ADNJ. UK research on the biology of aging. Exp Gerontol 2001;
37(1):1-7. PDF
de Grey ADNJ. Response to "telomere shortening with aging in human liver".
J Gerontol A Biol Sci Med Sci 2001; 56(6):B237-B238. PDF
de Grey ADNJ. HO2: the forgotten radical. DNA Cell Biol 2002; 21(4):251-257. PDF
de Grey ADNJ. Critique of the demographic evidence for "late-life
non-senescence". Biochem Soc Trans 2003; 31(2):452-454. PDF
de Grey ADNJ. A proposal for the overall structure of the mammalian
plasma membrane redox system. Protoplasma 2003; 221(1-2):3-9. PDF
de Grey ADNJ. Overzealous maximum-likelihood fitting falsely convicts the slope heterogeneity hypothesis. Exp Gerontol 2003; 38(8):921-923. PDF
de Grey ADNJ. Falsifying falsifications: the most critical task of theoreticians in biology. Medical Hypotheses 2004; 62(6):1012-1020. PDF
de Grey ADNJ. The unfortunate influence of the weather on the rate of aging: why human caloric restriction or its emulation may only extend life expectancy by 2-3 years. Gerontology 2005; 51(2):73-82. PDF
de Grey ADNJ. Gene therapy. In: Encyclopedia of Aging, Fourth Edition (R. Schulz et al., eds.), Springer, 2006, in press. PDF
de Grey ADNJ. Do accumulating nuclear mutations or epimutations influence mammalian aging over and above cancer? Mech Ageing Dev 2006, in press. PDF