Can we use some cancer cells’ need for iron against them?

Can we use some cancer cells’ need for iron against them?

Researchers from the University of California, San Francisco, found that cells with oncogenic KRAS mutations have increased levels of ferrous iron (Fe2+) that could, potentially, be used to “turn on” drugs that target cancer cells. The researchers’ findings could give new life to effective cancer drugs that fell out of favor because of the harm they cause to healthy cells. Adding an iron-activated trigger can make the difference.

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Join our longevity conversation on ELONgevity Discord

Join our longevity conversation on ELONgevity Discord

We are proud to announce that we are taking our mission to a new platform: Discord. We encourage you to visit our Elongevity Discord and join the conversation. We want to build an incubator for ideas and discussion for people who share our passion for longevity, cryptocurrency and space. And we’d be thrilled to see you there!

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Maybe Mom was right: Going outside to play can extend your life

Maybe Mom was right: Going outside to play can extend your life

A new Swedish study finds that women who actively get exposed to sunlight have a lower risk of cardiovascular disease than those who avoid it. The study assessed the differences in sun exposure as a risk factor for all mortality among more than 29,500 Swedish women enrolled in a melanoma research effort since the 1990s. Researchers found that women with active sun exposure habits had a lower risk for cardiovascular disease and non-cancer/non-cardiovascular disease death. Life expectancy among women who avoided the sun was up to 2.1 years shorter than for women who get more sun.

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No, you don’t need 10,000 steps in a day. Shorter walks still help you live longer.

No, you don’t need 10,000 steps in a day. Shorter walks still help you live longer.

The secret of that 10,000-step claim was revealed in the past decade, when enterprising reporters discovered that it was the product of a Japanese pedometer company’s marketing efforts, and not based on any scientific study. Despite that, many of us kept trudging, on the assumption that diligently walking 10,000 steps – about five miles – will help prevent age-related conditions like cardiovascular disease and stroke. New research – including studies published in The Lancet and JAMA Network Open – confirms the benefits of walking, but suggests those daily strolls can be a lot shorter and even more leisurely.

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New study suggests one secret to long life may be hibernation

New study suggests one secret to long life may be hibernation

University of California, Los Angeles scientists believe there is a link between hibernation and long life. They found that yellow-bellied marmots can virtually halt the aging process during the seven to eight months they spend hibernating each year. These rodents can live up to 15 years longer than expected for their body weight.

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Research shows it’s never too late to start exercising

Research shows it’s never too late to start exercising

Researchers found that the men and women who maintained or increased their physical fitness had overall better brain health. Their findings suggest that either approach to exercise is fine to improve physical fitness – and deliver lifespan-lengthening health.

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Cellular reprogramming: Modern medicine's new way of giving us a health upgrade

Cellular reprogramming: Modern medicine's new way of giving us a health upgrade

Skeptics of cellular regeneration often encourage researchers to slow down and be cautious. They say there is much we don’t know about the science – even, that it may be dangerous. But that science is incredibly promising. While much research remains to done, we would hate for excessive caution to needlessly delay scientific progress. Many researchers are working on cellular regeneration.

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Longevity research is a magnet for innovation–and innovative investors

Longevity research is a magnet for innovation–and innovative investors

For more than 100 years, most breakthroughs in medical care resulted from physicians conducting scientific studies that were backed by medical schools or pharmaceutical and medical device companies. It’s time for a change. Longevity science and forward-thinking innovators are redefining how medical research is done.

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MPrize helped mice live longer. Now it’s humans’ turn

MPrize helped mice live longer. Now it’s humans’ turn

The 2003 MPrize was important because it was the first competition to stimulate advancements in life extension therapies. Our initiatives now are more complex than extending the lives of mice. We collaborated with NASA on a competition to identify ways to grow human tissue so that some day deep-space voyagers will have the tools to grow organs for transplant during their years-long missions.

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Cell rejuvenation vs. longevity? I say tomato, you say toMAHto

Cell rejuvenation vs. longevity? I say tomato, you say toMAHto

An Endpoints News story recently explored a seeming disconnect between Altos Labs’ stated goals and what one of its noted researchers, Juan Carlos Izpisua, told the Spanish newspaper El Pais. He said that the world will be able to “predict, prevent and treat diseases and aging” within two decades.

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University College London Study

University College London Study

A study by University College London scientists has, for the first time, found a link between genes that regulate our cells and the human lifespan. The genes were previously found to extend lifespan in small organisms, such as fruit flies. The findings corroborate the work being done by Turn Biotechnologies, one of the companies in which Methuselah Foundation has invested.

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People are Noticing the Difference of Dogelon Mars

People are Noticing the Difference of Dogelon Mars

A new article in Digital Journal suggests that crypto, which is changing how commerce is conducted, may soon begin transforming how the larger world works, as well. We’re proud that the example it cites is Dogelon Mars’ ($ELON) collaboration with Methuselah Foundation taking the critical first step towards interplanetary space travel.

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2021 was a Great Year for Longevity Research

2021 was a Great Year for Longevity Research

After years of being regarded as a red-headed stepchild of science, longevity is where the research and investment action is. A new report by Longevity Technology shows a great roundup of highlights from throughout the year, including top scientific breakthroughs, big investments, and research about consumer attitudes.

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